The synergy/interaction-thread of nutrients

[LightLover]

There are a few synergies between nutrients I have read about.
(explanation: a synergy is when a nutrient works much stronger
if it is consumed in combination with another certain kind of other nutrient,
than it will work when taken on its own)

Does anyone know more, described in literature/publications, than the one's listed below?
I am especially interested if there are more "fat-synergies"

1. Broccoli & tomato (synergy: lutein & lycopene)
2. Avocado & tomato ((synergy: lutein & lycopene)
3. curcumine & (black?) pepper: very strong synergy, but I don't know which compounds
4. coconut & flaxseed/hempseed etc.. (synergy between coconutfat and the a-linoleenacid of the latter, which stimulates the conversion into
omega-3 fats.


LL

[LightLover]

*** A new synergy:

1a) sulphoraphane and apigenin :D
1b) sulphoraphane and broccoli :D

What about the following super-synergy-juice: tomato-broccoli-apple?
Something extra to be added for the taste?

---
LL
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The broccoli compound sulphoraphane and apigenin, a flavonoid found in fruits like apples and cherries as well as tea, appear to work together against cancer cells, according a new research to be published next month.

The in vitro study is part of a growing investigation into the potential synergy between different natural compounds to acheve greater protection against cancer than from one nutrient alone.
Dr Yongping Bao from the UK-based Institute of Food Research reported last year on an interaction between sulphoraphane and the antioxidant mineral selenium in inducing anticancer enzymes and inhibiting cancerous cell growth and tumour formation. The two food components were reported to be up to 13 times more powerful when put to work together than when used alone.
In the new study, Dr Bao reports that sulphoraphane, found in all brassica vegetables, also works in synergy with the polyphenol apigenin.

Apigenin is natural flavonoid present in fruits and vegetables such as apples, beans, broccoli, celery, cherries, grapes, leeks, onions, parsley and tomatoes, as well as plant-derived beverages like tea and wine.

Writing in the 9 September issue of Carcinogenesis (vol 25), Dr Bao and colleagues note that flavonoids have a number of different properties in vitro, including the induction of phase II enzymes, such as UDP-glucuronosyl transferases (UGT) and glutathione transferases (GST), two major phase II detoxifying enzymes. These enzymes delete genetically damaged cells before they become cancerous and detoxify carcinogens making them readily excretable.

Investigating the anticancer activity of sulphoraphane and apigenin in human intestinal cells, they found that apigenin induces UGT1A1 transcription four-fold. Sulphoraphane induced both UGT1A1, by almost four times, as well as GSTA1 (2.5-fold) in both dose- and time-dependent manners.

The combination of sulphoraphane and apigenin resulted in a synergistic induction of UGT1A1 mRNA up to 12-fold, they write. But both compounds acted through different signaling pathways, reveals the study, allowing for the synergistic effect.

More research is needed to better understand the mechanisms of compounds such as sulphoraphane in regulating gene expression during cancer formation. The IFR researchers are applying to carry out a human study.

US researchers have also studied how broccoli's glucosinolates and the lycopene found in tomatoes could work together to boost the cancer protection already known to be offered by each of the foods alone. This increasingly used approach aims to measure the complex interactions that take place in the overall diet rather than singling out specific nutrients.

In their study on rats, those fed a combination of tomatoes and broccoli had markedly less prostate tumour growth than rats who ate diets containing either food alone - and also less tumour growth than rats who ate diets containing specific cancer-fighting substances isolated from tomatoes and broccoli.

There may be many other compounds that act synergistically when combined in the human diet.

[LightLover]

ERROR !!

1b) sulphoraphane and broccoli

is wrong; should be:

1b) sulphoraphane and selenium


LL

[eatyourbroccoli]

so much for mono-eating eh? ;)

[LightLover]

Ah, you notice the hint..?:D

[luckitri]

Yes I got the hint also. But once again every Body is different and the human body has been known to save nutrients from one meal to the next when in its intelligent design, it knows that it needs them.

Thank you for this Lightlover, I had intuitively made coconut flax crackers just to try it, never having seen a recipe for it, it is like a dessert for me.

[LightLover]

Yes I got the hint also. But once again every Body is different and the human body has been known to save nutrients from one meal to the next when in its intelligent design, it knows that it needs them.

Thank you for this Lightlover, I had intuitively made coconut flax crackers just to try it, never having seen a recipe for it, it is like a dessert for me.
---
I agree in some way with you luckitri, I myself like to see it as following:

* I know form research that some combinations are much more effective than others;

* I try these combinations, and when they "feel good" I embrace them.
And they will even taste better, knowing the synergy of the nutrients!
* In this way the heart embraces the mind, it is both intuition and science
it is and/and, and not or/or.
* Of course I always keep doing things far away from the track, for fun..:)

LL
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[The Raw Alchemist]

I have studied nutrition for years at one time wanting to become a nutritionist. I came from the era of food combining at each meal to get the right amino acids to make a complete protein. Research has now shown that we have approximately a 70 gram amino acid pool floating around our bodies so it’s not necessary to eat amino acids in the same meal to get a complete protein. Seems logical this would be how the perfect design of our bodies is. Also goes to reason that if I only ate one kind of food that this amino acid pool would soon become deficient in some of its amino acids. Variety is key but as to how much and how often; its all speculation.

[LightLover]

I have studied nutrition for years at one time wanting to become a nutritionist. I came from the era of food combining at each meal to get the right amino acids to make a complete protein. Research has now shown that we have approximately a 70 gram amino acid pool floating around our bodies so it’s not necessary to eat amino acids in the same meal to get a complete protein. Seems logical this would be how the perfect design of our bodies is. Also goes to reason that if I only ate one kind of food that this amino acid pool would soon become deficient in some of its amino acids. Variety is key but as to how much and how often; its all speculation.

makes sense on itself this story, only a little point:

* most people have a "70 gram amino acid pool floating around our bodies ",
or maybe much more, because we eat to much protein;

* I doubt much people have a phytochemical pool in their body.
I don't know if these kind of pools exist for all these micro-nutrients?

But hey, for rawfooders all the rules are new and changed.:D
LL

[LightLover]

Raw alchemist:

In their study on rats, those fed a combination of tomatoes and broccoli had markedly less prostate tumour growth than rats who ate diets containing either food alone - and also less tumour growth than rats who ate diets containing specific cancer-fighting substances isolated from tomatoes and broccoli.

* But I must admit that maybe the rats have a worse digestive system
than human rawfooders, and that for the latter it can be possible that there
is a "nutrient-pool" in the body for micro-nutrients.

* But hey, who likes anyway broccoli juice without anything else in it?
I bet it tastes better with tomato and apple.

LL

[luckitri]

I for one hope to never make the mistake of broccoli juice again. Gas explosion!

[The Raw Alchemist]

LOL luckitri....ill keep that in mind.

[LightLover]

I for one hope to never make the mistake of broccoli juice again. Gas explosion!

hmm...this explosion undermines the story a little bit...:p



LL

[LightLover]

Synergy: Cayenne strongly supports other herbs

Taken from a thread about cayenne on this board:

Cayenne pepper is like TNT; it's like nitroglycerin; it blasts through all that
blockage to get to that area that's sick, taking with it all the vitamins and
minerals from the food you eat, and all the vital chemicals from the herbs you
take - all the way to the sick area.

http://www.therawdiet.com/cayenne.html - scroll down to read. Dr. Schulze's website is www.HerbDoc.com

LL

[LightLover]

Warning:


The specialist Dr SChulze advises not to take Cayenne in capsules.

Only as powder or tincture

LL

[LightLover]

* I have made the list more properly, and also found that the
good stuff in black pepper is "piperine".
LL :)

1. Broccoli/avocado & tomato (synergy: lutein & lycopene)
2. curcumine (turmeric root) & black pepper: very strong synergy,
between piperine (in black pepper) & curcumin (turmeric root)
3. coconut & flaxseed/hempseed etc.. (synergy between coconutfat and the a-linoleenacid of the latter, which stimulates the conversion into
omega-3 fats.
4. sulphoraphane* and apigenin: example: broccoli and apple
5. sulphoraphane* and selenium:
6. Any herb & Cayennepepper or other hot peppers

* this stuff is in any food of the BRASSICA-familiy.